Research progress on the Hippo-YAP signaling pathway mediated osteoimmunology in modulating implant osseointegration / 口腔疾病防治
Journal of Prevention and Treatment for Stomatological Diseases
; (12): 334-339, 2021.
Article
em Zh
| WPRIM
| ID: wpr-873682
Biblioteca responsável:
WPRO
ABSTRACT
@#Ideal osseointegration is intimately related to favorable osteoimmune properties around dental implants. An increasing number of in vitro and in vivo studies have indicated that the Hippo-YAP signaling pathway is involved in this biological process. In this article, the implicated roles of Hippo-YAP the signaling axis in peri-implant osteoimmunology were summarized by reviewing relevant evolving literature. The discrepancy concerning the Hippo-YAP signaling regulatory effect on osteogenesis and polarization direction were analyzed as well as propose the potential mechanism, which may be caused by the maturation of osteogenesis-related cells and heterogeneity of macrophages. More attention should be given to the requirements of promoting osteogenesis and patterns of regulating the immune microenvironment by Hippo-YAP in future studies.
Texto completo:
1
Índice:
WPRIM
Idioma:
Zh
Revista:
Journal of Prevention and Treatment for Stomatological Diseases
Ano de publicação:
2021
Tipo de documento:
Article