Prenatal Diagnosis of Tetralogy of Fallot Associated with Chromosome 22q11 Deletion
Journal of Korean Medical Science
;
: 125-128, 2002.
Artigo
em Inglês
| WPRIM
| ID: wpr-87466
ABSTRACT
Microdeletion of 22q11 is responsible for DiGeorge syndrome, velocardiofacial syndrome, congenital conotruncal heart defects, and related disorders. We report our experiences on prenatal diagnosis by fluorescence in situ hybridization (FISH) for 22q11 deletion in two fetuses with tetralogy of fallot. Karyotyping and FISH of the parents revealed that one fetus inherited the disease from maternal microdeletion. These findings suggest the importance of performing FISH in pregnancies with prenatally detected tetralogy of Fallot.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Diagnóstico Pré-Natal
/
Tetralogia de Fallot
/
Cromossomos Humanos Par 22
/
Ecocardiografia
/
Deleção Cromossômica
/
Hibridização in Situ Fluorescente
/
Doenças Fetais
Tipo de estudo:
Estudo diagnóstico
Limite:
Adulto
/
Feminino
/
Humanos
/
Gravidez
Idioma:
Inglês
Revista:
Journal of Korean Medical Science
Ano de publicação:
2002
Tipo de documento:
Artigo
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