Association Between Non-erosive Reflux Disease and High Risk of Obstructive Sleep Apnea in Korean Population
Journal of Neurogastroenterology and Motility
;
: 197-204, 2014.
Artigo
em Inglês
| WPRIM
| ID: wpr-87486
ABSTRACT
BACKGROUND/AIMS:
Obstructive sleep apnea is becoming more important in gastroesophageal reflux disease (GERD) patients. This study investigated the prevalence of high risk for obstructive sleep apnea in GERD patients in comparison with that in healthy controls using the Berlin Questionnaire. We also investigated the risk factors for obstructive sleep apnea in GERD patients.METHODS:
We enrolled 1,007subjects:
776 healthy controls, 115 individuals with erosive reflux disease, and 116 with non-erosive reflux disease. GERD was diagnosed and classified using endoscopy and a reflux questionnaire. The Berlin Questionnaire was used to evaluate obstructive sleep apnea.RESULTS:
More patients in the GERD group (28.2%) had higher risk for obstructive sleep apnea than healthy controls (20.4%, P = 0.036). More patients with non-erosive disease (32.8%) had higher risk for obstructive sleep apnea (OSA) than patients with erosive disease (20.9%) and controls (20.4%, P = 0.010). On multivariate analysis, non-erosive disease was a high risk factor for obstructive sleep apnea (odds ratio [OR], 1.82; P = 0.011). Age > or = 55 years (OR, 1.83; P or = 25 kg/m2) (OR, 2.76; P or = 55, and a high BMI are associated with high risk for OSA.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Berlim
/
Refluxo Gastroesofágico
/
Índice de Massa Corporal
/
Prevalência
/
Análise Multivariada
/
Inquéritos e Questionários
/
Fatores de Risco
/
Apneia Obstrutiva do Sono
/
Endoscopia
/
Esofagite
Tipo de estudo:
Estudo de etiologia
/
Estudo de prevalência
/
Fatores de risco
Limite:
Humanos
País/Região como assunto:
Europa
Idioma:
Inglês
Revista:
Journal of Neurogastroenterology and Motility
Ano de publicação:
2014
Tipo de documento:
Artigo
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