A Case of Clear Cell Hidradenoma with Aprocine and Eccrine Differentiation / 대한피부과학회지

ABSTRACT

Clear cell hidradenoma (CCH) is a rare benign tumor that shows differentiation toward the structure of a sweat gland. Recently, hidradenoma has been re-classified into apocrine and eccrine variants and CCH has been classified as apocrine differentiation. A 34-year-old man without any underlying diseases presented with an erythematous, papilliform, 1-cm exophytic nodule on the left neck that had been present for 3 years. Skin biopsy specimens were obtained by excision biopsy of his left neck. Histopathologic findings showed a well-circumscribed tumor composed of solid portions with polyhedral cells and clear cells, a tubular space with columnar cells, and decapitation secretion. Additionally, round, basophilic, poroid cells, tubular structures containing hyalinized material, and intercellular bridges were observed in the epidermis. Herein, we present a rare case of CCH with apocrine and eccrine differentiation.