Predictive Biomarkers of Immune-related Adverse Events Induced by Checkpoint Inhibitors in Malignancies / 中国医学科学院学报
Acta Academiae Medicinae Sinicae
; (6): 825-830, 2020.
Article
em Zh
| WPRIM
| ID: wpr-878685
Biblioteca responsável:
WPRO
ABSTRACT
While immune checkpoint inhibitors(ICIs)are effective and promising treatments for a variety of malignancies,they also have safety concerns,especially the immune-related adverse events(irAEs).Unlike the side effects of traditional chemotherapy and targeted therapy,irAEs are adverse events caused by immune activation after ICIs treatment and thus may involve almost every system of the body.Therefore,biomarkers for predicting irAEs after ICIs treatment are urgently needed.Here we review the currently available predictive biomarkers of irAEs.
Palavras-chave
Texto completo:
1
Índice:
WPRIM
Assunto principal:
Biomarcadores
/
Inibidores de Checkpoint Imunológico
/
Imunoterapia
/
Neoplasias
Tipo de estudo:
Prognostic_studies
Limite:
Humans
Idioma:
Zh
Revista:
Acta Academiae Medicinae Sinicae
Ano de publicação:
2020
Tipo de documento:
Article