Advances about perineuronal nets in the repair of nerve function after spinal cord injury / 中国骨伤
China Journal of Orthopaedics and Traumatology
;
(12): 91-96, 2021.
Artigo
em Chinês
| WPRIM
| ID: wpr-879412
ABSTRACT
Perineuronal nets (PNNs) is a complex network composed of highly condensed extracellular matrix molecules surrounding neurons. It plays an important role in maintaining the performance of neurons and protecting them from harmful substances. However, after spinal cord injury, PNNs forms a physical barrier that surrounds the neuron and limits neuroplasticity, impedes axonal regeneration and myelin formation, and promotes local neuroinflammatory uptake. This paper mainly describes the composition and function of PNNs of neurons and its regulatory effects on axonal regeneration, myelin formation and neuroinflammation after spinal cord injury.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Medula Espinal
/
Traumatismos da Medula Espinal
/
Axônios
/
Matriz Extracelular
/
Regeneração Nervosa
/
Plasticidade Neuronal
/
Neurônios
Limite:
Humanos
Idioma:
Chinês
Revista:
China Journal of Orthopaedics and Traumatology
Ano de publicação:
2021
Tipo de documento:
Artigo
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