Research progress on the correlation between abnormal sperm DNA methylation and semen quality / 中华医学遗传学杂志
Chinese Journal of Medical Genetics
;
(6): 188-193, 2021.
Artigo
em Chinês
| WPRIM
| ID: wpr-879553
ABSTRACT
DNA methylation as an important aspect of epigenetics plays an important role in spermatogenesis and embryonic development. In recent years, researchers have found that male infertility, in particular abnormal semen quality, is related to abnormal DNA methylation. To further delineate the pathogenesis of male infertility and inspire new ideas for the treatment of male infertility, a comprehensive review over the correlation between abnormal methylation of imprinted genes, repetitive DNA elements and non-imprinted genes, semen quality (including sperm count, morphology, and vitality) and male infertility is provided.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Contagem de Espermatozoides
/
Espermatogênese
/
Espermatozoides
/
Metilação de DNA
/
Análise do Sêmen
/
Infertilidade Masculina
Limite:
Humanos
/
Masculino
Idioma:
Chinês
Revista:
Chinese Journal of Medical Genetics
Ano de publicação:
2021
Tipo de documento:
Artigo
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