Intracerebroventricular drug administration
Translational and Clinical Pharmacology
;
: 117-124, 2017.
Artigo
em Inglês
| WPRIM
| ID: wpr-87967
ABSTRACT
Among the various routes of drug administration, perhaps the least studied is intracerebroventricular (ICV) administration. This route has been shown to be particularly useful in administering to the central nervous system (CNS) drugs that do not cross the blood-brain barrier readily. As such, the ICV route is a valuable option for providing therapeutic CNS drug concentrations to treat patients with CNS infectious and neoplastic diseases. This route of drug administration also has the advantage of minimizing systemic toxicity.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Farmacocinética
/
Barreira Hematoencefálica
/
Sistema Nervoso Central
/
Meningite
Limite:
Humanos
Idioma:
Inglês
Revista:
Translational and Clinical Pharmacology
Ano de publicação:
2017
Tipo de documento:
Artigo
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