Analysis of the Different Therapeutic Effects in 21 Ph / 中国实验血液学杂志
Journal of Experimental Hematology
;
(6): 38-42, 2021.
Artigo
em Chinês
| WPRIM
| ID: wpr-880028
ABSTRACT
OBJECTIVE@#To analyze the outcomes of the children suffered from philadelphia chromosome positive acute lymphoblastic leukemia (Ph@*METHODS@#21 cases of firstly diagnosed Ph@*RESULTS@#Among 21 patients, 17 were male and 4 were female with a median age of 8 years old (range, 4-12 years), the median follow-up time was 30 moths (range, 10-133 months). All the patients were treated with chemotherapy induced by the high-risk project of CCLG-ALL 2008. Among 14 patients treated with TKI plus chemotherapy, nine patients achieved complete remission. During 3 months after treatment, patients without complete molecular response or with the second complete remission and intensity desire of transplantation were treated with allo-HSCT, among 9 patients with allo-HSCT, six patients achieved long term survival.@*CONCLUSION@#At TKI era, TKI combined with strong chemotherapy can make Ph
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Cromossomo Filadélfia
/
Estudos Retrospectivos
/
Transplante de Células-Tronco Hematopoéticas
/
Inibidores de Proteínas Quinases
/
Leucemia-Linfoma Linfoblástico de Células Precursoras
Tipo de estudo:
Estudo observacional
Limite:
Idoso
/
Criança
/
Feminino
/
Humanos
/
Lactente
/
Masculino
Idioma:
Chinês
Revista:
Journal of Experimental Hematology
Ano de publicação:
2021
Tipo de documento:
Artigo
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