Research progress in building and applying cardiomyocytes injury model / 中南大学学报(医学版)
Journal of Central South University(Medical Sciences)
;
(12): 1223-1227, 2020.
Artigo
em Inglês
| WPRIM
| ID: wpr-880589
ABSTRACT
Cardiomyocytes injury model has been widely used in the study for the molecular mechanism of cardiovascular diseases and drug action. It is very important to select the appropriate model due to the different formation mechanisms for various models. Clinical cardiovascular pathological change is relatively complex. Currently used models according to the characteristics of clinical cardiovascular diseases mainly include hydrogen peroxide-induced myocardial cell damage model, hypoxia reoxygenation injury model, adriamycin-induced myocardial cell damage model, high sugar high fat-induced myocardial cell damage model, and isoprenaline-induced myocardial cell damage model. Every model has its advantages as well as its disadvantages. The suitable model of myocardial cell injury can be selected according to the research purpose.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Pesquisa
/
Traumatismo por Reperfusão Miocárdica
/
Hipóxia Celular
/
Ratos Sprague-Dawley
/
Miócitos Cardíacos
/
Miocárdio
Tipo de estudo:
Estudo prognóstico
Limite:
Animais
Idioma:
Inglês
Revista:
Journal of Central South University(Medical Sciences)
Ano de publicação:
2020
Tipo de documento:
Artigo
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