Research advances in add-on treatment for negative symptoms and cognitive dysfunction in schizophrenia / 中南大学学报(医学版)
Journal of Central South University(Medical Sciences)
; (12): 1457-1463, 2020.
Article
em En
| WPRIM
| ID: wpr-880607
Biblioteca responsável:
WPRO
ABSTRACT
Antipsychotic medication is the primary treatment for schizophrenia, which is effective on ameliorating positive symptoms and can reduce the risk of recurrence, but it has limited efficacy for negative symptoms and cognitive dysfunction. The negative symptoms and cognitive dysfunction seriously affects the life quality and social function for the patients with schizophrenia. Currently, there is plenty evidence that antipsychotic drugs combined with adjuvant therapy drugs can effectively improve the negative symptoms and cognitive dysfunction. These drugs include anti-oxidants, nicotinic acetylcholine receptors and neuro-inflammatory drugs (anti-inflammatory drugs, minocycline), which show potential clinical effects.
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Texto completo:
1
Índice:
WPRIM
Assunto principal:
Esquizofrenia
/
Antipsicóticos
/
Disfunção Cognitiva
/
Anti-Inflamatórios
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Minociclina
Tipo de estudo:
Diagnostic_studies
Limite:
Humans
Idioma:
En
Revista:
Journal of Central South University(Medical Sciences)
Ano de publicação:
2020
Tipo de documento:
Article