Mechanical heart valve thrombosis during pregnancy under non / 中南大学学报(医学版)
Journal of Central South University(Medical Sciences)
;
(12): 207-211, 2021.
Artigo
em Inglês
| WPRIM
| ID: wpr-880645
ABSTRACT
Anticoagulation drugs should be used for patients with mechanical heart valve (MHV) in case of potential risk of thrombosis. Pregnant women with MHV have to change therapies due to teratogenic effect of some anti-coagulation drugs. European Society of Cardiology clinical guidelines for the management of cardiovascular diseases during pregnancy gives specific suggestions for anticoagulation therapy.We have treated 2 patients with mechanical heart valve thrombosis (MVT) during pregnancy One received low molecular weight heparin (LMWH) throughout the pregnancy and developed MVT at the third trimester of pregnancy; one developed MVT at the first trimester when replacing vitamin K antagonists (VKA) with LMWH. These patients raised secondary reflection on the balance between clinical guideline and personalized medicine. During LMWH therapy, we should dynamically monitor patients' anti-activated factor X (anti-Xa) level to evaluate coagulation function during pregnancy. When a pregnant woman with MHV develops symptoms of acute heart failure, stuck mechanical valve should be paid attention to and surgery should be promptly performed if necessary.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Complicações Cardiovasculares na Gravidez
/
Trombose
/
Próteses Valvulares Cardíacas
/
Heparina de Baixo Peso Molecular
/
Valvas Cardíacas
/
Anticoagulantes
Tipo de estudo:
Guia de Prática Clínica
Limite:
Feminino
/
Humanos
/
Gravidez
Idioma:
Inglês
Revista:
Journal of Central South University(Medical Sciences)
Ano de publicação:
2021
Tipo de documento:
Artigo
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