Study on the secondary metabolites of grasshopper-derived fungi Arthrinium sp. NF2410 / 中国天然药物
Chinese Journal of Natural Medicines (English Ed.)
;
(6): 957-960, 2020.
Artigo
em Inglês
| WPRIM
| ID: wpr-881042
ABSTRACT
Two new 2-carboxymethyl-3-hexyl-maleic anhydride derivatives, arthrianhydride A (1) and B (2), along with three known compounds 3-5, were isolated from the fermentation broth of a grasshopper-associated fungus Arthrinium sp. NF2410. The structures of new compounds 1 and 2 were determined based on the analysis of the HR-ESI-MS and NMR spectroscopic data. Furthermore, compounds 1 and 2 were evaluated on inhibitory activity against the enzyme SHP2 and both of them showed moderate inhibitory activity against SHP2.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Produtos Biológicos
/
Estrutura Molecular
/
Inibidores Enzimáticos
/
Proteína Tirosina Fosfatase não Receptora Tipo 11
/
Metabolismo Secundário
/
Fungos
/
Gafanhotos
/
Anidridos
Limite:
Animais
Idioma:
Inglês
Revista:
Chinese Journal of Natural Medicines (English Ed.)
Ano de publicação:
2020
Tipo de documento:
Artigo
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