Prognostic Value of Day 3 Inhibin-B on Assisted Reproductive Technology Outcome / 대한불임학회지
Korean Journal of Fertility and Sterility
; : 217-223, 1997.
Article
em Ko
| WPRIM
| ID: wpr-88107
Biblioteca responsável:
WPRO
ABSTRACT
This study was performed to determine if women with day 3 serum inhibin-B concentrations or = 45pg/ml, independant of day 3 FSH, E2 and patient age. From Jan 1996 to Dec 1996, 16 volunteers patients who underwent 25 IVF cycles with luteal phase GnRH agonist suppression and HMG stimulation were allocated to the study group. We evaluated day 3 serum inhibits-B, FSH, E2, peak E2, cancellation rate per initiated cycle (%) and clinical pregnancy rate per initiated cycle (%) according to the above two groups and independent of patient age, day 3 FSH, day 3 E2 and all of above combined. Women with day 3 serum inhibin-B > or =45pg/m1 demonstrated higher average day 3 inhibits-B level, clinical pregnancy rate per initiated cycle (20.3+/-2.5 pg/ml vs 80.9+/- 5.0pg/ml, p or =45pg/ml and age or =45pg/ml and day 3 FSH or =45pg/ml and day 3 E2 or =45pg/ml, age<40 year, day 3 FSH<15mIU/ml and day 3 E2<50pg/m1 demonstrated higher pregnancy rate per initiated cycle (30.0% vs 10.8%, p<0.05) and lower day 3 FSH level, cancellation rate per initiated cycle (6.8+/-0.6 mIU/ml vs 8.4+/-0.9 mIU/ml, p<0.05; 1.5% vs 7.8%, p<0.05). Therefore women with low day 3 serum inhibits-B concentrations demonstrate a poorer response to ovulation induction and are less likely to conceive a clinical pregnancy though ART relative to women with high day 3 inhibits-B and day 3 serum inhibin-B, in addition to a day 3 FSH, E2 and patient age, appears helpful in prediction in IVF-ET outcome.
Texto completo:
1
Índice:
WPRIM
Assunto principal:
Indução da Ovulação
/
Voluntários
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Hormônio Liberador de Gonadotropina
/
Taxa de Gravidez
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Técnicas de Reprodução Assistida
/
Sistema Internacional de Unidades
/
Fase Luteal
Tipo de estudo:
Prognostic_studies
Limite:
Female
/
Humans
/
Pregnancy
Idioma:
Ko
Revista:
Korean Journal of Fertility and Sterility
Ano de publicação:
1997
Tipo de documento:
Article