Detecting 41 mineral elements in human whole blood by inductively coupled plasma-mass spectrometry / 中国职业医学
China Occupational Medicine
;
(6): 91-95, 2020.
Artigo
em Chinês
| WPRIM
| ID: wpr-881872
ABSTRACT
OBJECTIVE:
To establish a method for detecting 41 mineral elements such as beryllium, magnesium and calcium in whole blood by inductively coupled plasma-mass spectrometry(ICP-MS).METHODS:
After the whole blood samples were diluted 1∶20 in a mixed solution containing 0.10% Triton X-100 and 0.50% nitric acid, 41 mineral elements in whole blood samples such as beryllium, magnesium and calcium were determined by the ICP-MS, using scandium, rhodium and iridium as the internal standard elements.RESULTS:
The linear correlation coefficient was >0.999 0 in these 41 elements such as beryllium, magnesium and calcium in the whole blood. The detection limit was 0.006-247.000 μg/L, the quantification lower limit was 0.020-822.000 μg/L. The recovery rate of standard addition was 84.00%-109.40%. The within-run and between-run relative standard deviation were 0.66%-7.34% and 0.56%-8.22%, respectively. The samples could be stored at-20 ℃ for at least 14 days.CONCLUSION:
This method is simple, rapid and sensitive, with good precision and reliable results. It can be used for detecting multiple mineral elements in whole blood of normal and occupational population.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Idioma:
Chinês
Revista:
China Occupational Medicine
Ano de publicação:
2020
Tipo de documento:
Artigo
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