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Research progress on the relationship between pentraxin 3 and Henoch-Schonlein purpura / 中华实用儿科临床杂志
Article em Zh | WPRIM | ID: wpr-882901
Biblioteca responsável: WPRO
ABSTRACT
Henoch-Schonlein purpura (HSP) is one of the most common clinical manifestations of systemic small vasculitis in children with non-thrombocytopenic, and mainly manifested as skin purpura, arthritis, gastrointestinal symptoms and Henoch-Schonlein purpura nephritis (HSPN). The severity of renal involvement is the main factor determining the long-term prognosis of children with HSP.Studies have revealed that the determination of pentraxin 3 (PTX3) in serum can be used for early diagnosis of HSPN and prediction of renal injury.In this paper, the origin, gene and protein structure, function, potential relationship and mechanism of action between PTX3 and HSP were discussed, so as to provide new ideas for the early diagnosis and treatment of HSPN.
Texto completo: 1 Índice: WPRIM Tipo de estudo: Prognostic_studies / Screening_studies Idioma: Zh Revista: Chinese Journal of Applied Clinical Pediatrics Ano de publicação: 2021 Tipo de documento: Article
Texto completo: 1 Índice: WPRIM Tipo de estudo: Prognostic_studies / Screening_studies Idioma: Zh Revista: Chinese Journal of Applied Clinical Pediatrics Ano de publicação: 2021 Tipo de documento: Article