Four new lanostane triterpenoids from latex of Euphorbia resinifera / 中国中药杂志
China Journal of Chinese Materia Medica
;
(24): 4744-4748, 2021.
Artigo
em Chinês
| WPRIM
| ID: wpr-888180
ABSTRACT
Four new lanostane triterpenoids, 3β-hydroxy-12α-methoxylanosta-7,9(11),24-triene(1), 3β-hydroxy-12α-methoxy-24-methylene-lanost-7,9(11)-dien(2), 3,7-dioxo-lanosta-8,24-diene(3), and 3,7-dioxo-24-methylene-lanost-8-en(4), were isolated from the latex of Euphorbia resinifera with a variety of chromatography methods. Their structures were elucidated based on spectroscopic data and/or comparison with the data reported in previous research. Compounds 1, 2, and 4 showed moderate inhibition of LPS-induced NO production by RAW264.7, with IC_(50) of 30.4, 37.5, and 28.3 μmol·L~(-1), respectively.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Esteroides
/
Triterpenos
/
Estrutura Molecular
/
Euphorbia
/
Látex
Idioma:
Chinês
Revista:
China Journal of Chinese Materia Medica
Ano de publicação:
2021
Tipo de documento:
Artigo
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