Air pollution and children's health-a review of adverse effects associated with prenatal exposure from fine to ultrafine particulate matter
Environmental Health and Preventive Medicine
;
: 72-72, 2021.
Artigo
em Inglês
| WPRIM
| ID: wpr-888606
ABSTRACT
BACKGROUND@#Particulate matter (PM), a major component of ambient air pollution, accounts for a substantial burden of diseases and fatality worldwide. Maternal exposure to PM during pregnancy is particularly harmful to children's health since this is a phase of rapid human growth and development.@*METHOD@#In this review, we synthesize the scientific evidence on adverse health outcomes in children following prenatal exposure to the smallest toxic components, fine (PM@*RESULTS@#Maternal exposure to fine and ultrafine PM directly and indirectly yields numerous adverse birth outcomes and impacts on children's respiratory systems, immune status, brain development, and cardiometabolic health. The biological mechanisms underlying adverse effects include direct placental translocation of ultrafine particles, placental and systemic maternal oxidative stress and inflammation elicited by both fine and ultrafine PM, epigenetic changes, and potential endocrine effects that influence long-term health.@*CONCLUSION@#Policies to reduce maternal exposure and health consequences in children should be a high priority. PM
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Tamanho da Partícula
/
Placenta
/
Efeitos Tardios da Exposição Pré-Natal
/
Doenças Respiratórias
/
Resultado da Gravidez
/
Doenças Cardiovasculares
/
Saúde da Criança
/
Estresse Oxidativo
/
Exposição Materna
/
Poluentes Atmosféricos
Limite:
Animais
/
Feminino
/
Humanos
/
Masculino
/
Gravidez
Idioma:
Inglês
Revista:
Environmental Health and Preventive Medicine
Ano de publicação:
2021
Tipo de documento:
Artigo
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