Identification and characterization of a novel elastase inhibitor from Hirudinaria manillensis / 中国天然药物
Chinese Journal of Natural Medicines (English Ed.)
;
(6): 540-544, 2021.
Artigo
em Inglês
| WPRIM
| ID: wpr-888783
ABSTRACT
A large number of protease inhibitors have been found from leeches, which are essential in various physiological and biological processes. In the curret study, a novel elastase inhibitor was purified and characterized from the leech of Hirudinaria manillensis, which was named HMEI-A. Primary structure analysis showed that HMEI-A belonged to a new family of proteins. HMEI-A exerted inhibitory effects on elastase and showed potent abilities to inhibit elastase with an inhibition constant (K
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Inibidores de Proteases
/
Elastase Pancreática
/
Proteínas
/
Sequência de Aminoácidos
/
Sanguessugas
Limite:
Animais
Idioma:
Inglês
Revista:
Chinese Journal of Natural Medicines (English Ed.)
Ano de publicação:
2021
Tipo de documento:
Artigo
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