Medullary thyroid carcinoma: a 30-year experience at one institution in Korea
Annals of Surgical Treatment and Research
;
: 278-287, 2016.
Artigo
em Inglês
| WPRIM
| ID: wpr-89529
ABSTRACT
PURPOSE:
The objective of this study was to review the clinical outcome and prognosis of patients with sporadic and hereditary medullary thyroid cancer (MTC) who were treated at a single tertiary hospital in Korea.METHODS:
We retrospectively reviewed the case files of 85 patients treated from August 1982 to February 2012.RESULTS:
In all, 65 patients (76.5%) had sporadic MTC and 20 patients (23.5%) had hereditary MTC. Patients in the sporadic group were older than in the hereditary group (P < 0.001). However, the hereditary group had more tumor multiplicity (P < 0.001) and bilaterality (P < 0.001). Neither survival rate was significantly different between the sporadic and hereditary groups (P = 0.775 and P = 0.866). By multivariate analysis, distant metastasis was a significant prognostic factor for overall and progression-free survival.CONCLUSION:
In general, patients with MTC have favorable outcomes. Distant metastasis appears to be the strongest predictor of overall and progression-free survival.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Prognóstico
/
Glândula Tireoide
/
Neoplasias da Glândula Tireoide
/
Análise Multivariada
/
Taxa de Sobrevida
/
Estudos Retrospectivos
/
Intervalo Livre de Doença
/
Centros de Atenção Terciária
/
Coreia (Geográfico)
/
Metástase Neoplásica
Tipo de estudo:
Estudo observacional
/
Estudo prognóstico
Limite:
Humanos
País/Região como assunto:
Ásia
Idioma:
Inglês
Revista:
Annals of Surgical Treatment and Research
Ano de publicação:
2016
Tipo de documento:
Artigo
Similares
MEDLINE
...
LILACS
LIS