Erectile Dysfunction in Hemodialysis Patients / 대한신장학회잡지

ABSTRACT

PURPOSE: Erectile dysfunction(ED) is a common problem in men with end-stage renal disease(ESRD). The present study was aimed at investigating the prevalence and risk factors of ED among patients receiving chronic hemodialysis. METHODS: The presence and severity of ED were assessed among 48 ESRD patients using the self-administered International Index of Erectile Function-5 (IIEF-5). Logistic regression was used to examine and test associations between ED and other medical conditions. RESULTS: The mean age was 57.9+/-11.9 years and the cause of ESRD was diabetes mellitus(47.9%), unknown cause(29.2%) and hypertension(16.7%). All subjects had ED. The proportions reporting mild ED, mild/moderate ED, moderate ED and severe ED were 8.3%, 18.8%, 18.8% and 54.2%, respectively. Age, diabetes mellitus, Karnofsky Index, serum albumin and creatinine levels were statistically correlated with ED. But, a multivariable logistic regression analysis demonstrated age(odds ratio [OR]=12.254, 95% confidence interval [CI] 2.02 to 74.32, p=0.006) and nitrates administration(OR=11.85, 95% CI 1.06 to 132.5, p=0.045) to be independently associated with the presence of severe ED. CONCLUSION: ED is extremely prevalent among hemodialysis patients. Increasing age and medical conditioning in which nitrates should be administered are associated with higher prevalence of severe ED.