The Surgical Results of Stage I Lung Cancer / 대한흉부외과학회지
The Korean Journal of Thoracic and Cardiovascular Surgery
;
: 982-987, 1998.
Artigo
em Coreano
| WPRIM
| ID: wpr-90392
ABSTRACT
BACKGROUND:
Surgical resection is the standad therapy for the stage I lung cancer. We analysed the risk facturs of stage I lung cancer patent and tryed to establish more effective and aggressive treatment modality. MATERIALS ANDMETHODS:
A detailed analysis was undertaken to evaluate the surgical results and to define the risk factors associated with the recurrence and the survival time in 146 consecutive patients with stage I lung cancer who were diagnosed, and resected at Yonsei Medical Center from January 1990 to December 1996.RESULTS:
There were 115 males and 31 females. Their ages ranged from 27 to 79 years (mean age58.9+/-9.3 years). The histologic types were squamous carcinoma in 72 cases (49.3%) and adenocarcinoma in 45 cases (30.8%). A pulmonary resection and mediastinal lymph node dissection were done in all cases. A lobectomy was performed in 96 cases (65.7%) and a pneumonectomy in 48 cases (32.9%). There were 5 operative mortalities (3.4%) and complications occured in 24 cases (16.5%). The overall 5-year survival was 64.1%, and survival time did not depend on the type of operation or histologic type. Significant predictors of decreased survival were visceral pleural invasion (p=0.0079), T2 lesion (p=0.0462), and tumor size (> or =5 cm) in adenocarcinoma (p=0.0472). The overall incidence of recurrence was 33.3% (47 cases; local or regional 6.4%, distant 26.9%). Almost all recurrences (44cases) occurred in T2 lesions. The distant organs that failed were the contralateral lung in 13 patients, the brain in 12, the bone in 10, and other organs in 3.CONCLUSIONS:
even in stage I lung cancer, we suggest that postoperative adjuvant therapy is recommended in patients with poor prognostic factors such as visceral pleural invasion, T2 lesions, and a tumor size (> or =5 cm) in the adenocarcinoma.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Pneumonectomia
/
Recidiva
/
Encéfalo
/
Carcinoma de Células Escamosas
/
Adenocarcinoma
/
Incidência
/
Fatores de Risco
/
Mortalidade
/
Pulmão
/
Neoplasias Pulmonares
Tipo de estudo:
Estudo de etiologia
/
Estudo de incidência
/
Estudo prognóstico
/
Fatores de risco
Limite:
Feminino
/
Humanos
/
Masculino
Idioma:
Coreano
Revista:
The Korean Journal of Thoracic and Cardiovascular Surgery
Ano de publicação:
1998
Tipo de documento:
Artigo
Similares
MEDLINE
...
LILACS
LIS