Association of dietary niacin intake with metabolic syndromeamong adults in Zhejiang Province / 预防医学

ABSTRACT

Objective @#To explore the association of dietary niacin intake and metabolic syndrome ( MS ) and its components among adults in Zhejiang Province, so as to provide the reference for dietary intervention of MS.@*Methods@#Using the multi-stage cluster random sampling method, the permanent residents aged 18 years and above were selected and investigated by a questionnaire developed by China Center for Disease Control and Prevention. Their waist circumference, blood pressure, glucose and lipid were measured. The daily dietary niacin intake of each person were calculated by "24-hour dietary review for 3 consecutive days", and divided into Q1, Q2, Q3 and Q4 groups according to quartiles. The multivariate logistic regression model was used to analyze the association of niacin intake with the risks of MS and its components. @*Results@#Among 2 438 participants, 871 cases with MS were detected, with a detection rate of 35.73%. The multivariate logistic regression analysis showed that compared with niacin intake Q1 group, Q2 ( OR=0.741, 95%CI 0.561-0.978 ) and Q4 group ( OR=0.679, 95%CI 0.487-0.947 ) had a lower risk of MS, Q2 ( OR=0.688, 95%CI 0.516-0.919 ) and Q4 group ( OR=0.678, 95%CI 0.479-0.960 ) had a lower risk of abdominal obesity, Q4 group ( OR=0.721, 95%CI 0.536-0.969 ) had a lower risk of hyperglycemia. Further stratificating by gender, compared with niacin intake Q1 group, Q2 ( OR=0.664, 95%CI 0.453-0.972 ) and Q3 group ( OR=0.646, 95%CI 0.432-0.965 ) in women had a lower risk of MS, Q2 (OR=0.667, 95%CI 0.460-0.967) and Q3 group ( OR=0.607, 95%CI 0.408-0.902 ) had a lower risk of abdominal obesity; Q2 group ( OR=1.836, 95%CI 1.202-2.805 ) in men had a higher risk of low high-density lipoprotein cholesterol.@*Conclusion@#Niacin intake is associated with an increased risk of MS, abdominal obesity and hyperglycemia.