Oxaliplatin-Induced Immune-Mediated Thrombocytopenia: A Case Report / Journal of the Korean Cancer Association, 대한암학회지
Cancer Research and Treatment
;
: 949-953, 2015.
Artigo
em Inglês
| WPRIM
| ID: wpr-90542
ABSTRACT
Oxaliplatin is a third-generation platinum derivative used for metastatic or advanced colorectal cancer treatment. Although myelosuppression is the most common cause of oxaliplatin-induced thrombocytopenia, rare cases of oxaliplatin-induced immune-mediated thrombocytopenia are reported. We report a case of a 57-year-old woman with colon cancer who developed gum bleeding and petechiae after oxaliplatin infusion. Laboratory tests revealed grade 4 thrombocytopenia and grade 4 neutropenia. She recovered from the thrombocytopenia and accompanying neutropenia within 4 days with no recurrence following discontinuation of oxaliplatin. Physicians need to be aware of the risk of severe acute thrombocytopenia following oxaliplatin administration.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Platina
/
Púrpura
/
Recidiva
/
Trombocitopenia
/
Neoplasias Colorretais
/
Neoplasias do Colo
/
Gengiva
/
Hemorragia
/
Neutropenia
Limite:
Feminino
/
Humanos
Idioma:
Inglês
Revista:
Cancer Research and Treatment
Ano de publicação:
2015
Tipo de documento:
Artigo
Similares
MEDLINE
...
LILACS
LIS