Advance in Study on Classic Prescription Qingjin Huatantang / 中国实验方剂学杂志

ABSTRACT

Qingjin Huatanpang， first contained in Yixue Tongzhi， was composed of eleven medicinal materials of Scutellariae Radix， Gardeniae Fructus， Fritillariae Thunbergii Bulbus， Mori Cortex， Trichosanthis Semen Tostum， Citri Exocarpium Rubrum， Platycodonis Radix， Ophiopogonis Radix （core removed）， Anemarrhenae Rhizoma， Poria and Glycyrrhizae Radix et Rhizoma. It is a classic prescription created by YE Wen-ling in Ming dynasty for treating pulmonary disease with phlegm-heat obstructing lung syndrome. With the significant functions of clearing heat and moistening lung， reducing phlegm and relieving cough， it has been included in the "Classic Catalogue of Ancient Classics （First Batch）". Modern pharmacological studies have shown that Qingjin Huatantang has multiple activities such as relieving cough and eliminating phlegm， anti-inflammatory， bronchodilation， and immunoregulatory， and now it is commonly used for treating infectious lung diseases， such as acute exacerbation of chronic obstructive pulmonary disease， community acquire pneumonia， bronchiectasis， acute and chronic bronchitis in a form of its modified prescription or its combined use with western medicine， consistent with the clinical application in ancient times. According to the literatures on the study of Qingjin Huatantang published in recent years， this paper summed up the historical evolution， compatibility analysis， chemistry constituents， quality control， advances in pharmacology research， and clinical uses， which can provide theoretical and experimental data reference for further research and development， and proposed to establish a biological activity assay for quality control based on the pharmacological effect such as immunoregulatory activity， which can improve its quality control method and provide a reference for other famous classical formulas.