Progress of MICB/NKG2D signaling pathway in immune escape / 国际儿科学杂志
International Journal of Pediatrics
;
(6): 584-588, 2021.
Artigo
em Chinês
| WPRIM
| ID: wpr-907283
ABSTRACT
Natural killer group 2 member D(NKG2D) is an immune receptor expressed by NK cells that recognizes the human major histocompatibility complex class I polypetide-related chain(MIC) A/B on the cell surface.The interaction between NKG2D and MICA/B plays an important role in the immunosurveillance of viruses infection and cancers.In this article, we review the research progress of the MICB/NKG2D signaling pathway in immune escape including three parts down-regulation of membrane-bound MICB, increase of secretory MICB, and polymorphism of MICB genes.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Idioma:
Chinês
Revista:
International Journal of Pediatrics
Ano de publicação:
2021
Tipo de documento:
Artigo
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