Clinical analysis of community-acquired pneumonia in hospitalized children complicated with infectious exanthems / 国际儿科学杂志

ABSTRACT

Objective:To analyze the clinical characteristics of community acquired pneumonia in hospitalized children with infectious exanthems and to accumulate clinical experience in the diagnosis and treatment.Methods:The data of the community acquired pneumonia patients with infectious exanthems in Oingdao Women and Children′s Hospital were collected retrospectively from September 2013 to August 2020 and the clinical characteristics were analyzed.Results:A total of 455 cases were included, and there were 273 boys(60.0%)and 182 girls(40.0%). A total of 106 cases were grouped into the severe group(23.3%)and 349 cases were grouped into the non-severe group(76.7%). The median age was 16.0(9.0, 42.0)months.The exanthems occurred in day(6.9±5.2)d after the beginning of pneumonia.The duration of exanthems was(6.0±3.1)days.The exanthems was polymorphic and non-specific.The detection rate of influenza B virus was highest, including 91 cases(20.0%), followed by 85 cases of MP infection(18.7%), 50 cases(11.0%)of EBV reactivation infection.The median age, hospitalization time, fever time, exanthems appearance time, exanthems duration and the rate of the rash appears in the second fever course, CRP elevation, PCT elevation, IgE elevation, MP infection and reactivation of EB virus in the severe group were higher than those of non-severe group, and the differences were statistically significant( U=13 467.0, t=6.500, 4.923, 3.098, 2.998, χ2=13.445, 15.391, 8.208, 5.313, 29.839, 13.474, P<0.05). Multivariate logistic analysis showed that poor general conditions, extrapulmonary complications, decreased respiratory tone and recurrent fever accompanied by exanthems were independent risk factors. Conclusion:A non-specific infective rash associated with the course of the hospitalized CAP has some implications for the assessment of severity and etiology.