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Insights into immune mechanisms of ocular graft-versus-host disease / 中华实验眼科杂志
Chinese Journal of Experimental Ophthalmology ; (12): 1017-1020, 2021.
Artigo em Chinês | WPRIM | ID: wpr-908623
ABSTRACT
Ocular graft-versus-host disease (GVHD) is a major complication of hematopoietic stem cell transplantation (HSCT). However, the diagnostic criteria for ocular GVHD are controversial and mainly based on clinical experience.Objective and reliable diagnostic parameters for this disease are limited.As a result, most patients can not get early diagnosis and effective management.Tear cytokine profile analysis is a safe, convenient and noninvasive examination which reflects immune mechanisms of systemic and ocular diseases.Levels of certain cytokines in tear can serve as specific biomarkers of GVHD and thus have the potential to act as accurate diagnostic and prognostic tools.In this article, the current status of ocular GVHD diagnosis was summarized, the role of cytokines in immune mechanism and diagnosis of ocular GVHD were reviewed.

Texto completo: DisponíveL Índice: WPRIM (Pacífico Ocidental) Tipo de estudo: Estudo prognóstico / Estudo de rastreamento Idioma: Chinês Revista: Chinese Journal of Experimental Ophthalmology Ano de publicação: 2021 Tipo de documento: Artigo

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Texto completo: DisponíveL Índice: WPRIM (Pacífico Ocidental) Tipo de estudo: Estudo prognóstico / Estudo de rastreamento Idioma: Chinês Revista: Chinese Journal of Experimental Ophthalmology Ano de publicação: 2021 Tipo de documento: Artigo