Research progress on the effect of high-fat diet on intestinal homeostasis via microbial metabolites / 中华临床营养杂志

ABSTRACT

Intestinal homeostasis is affected by many factors such as genetics, environment, and eating habits. High-fat diet, as one of the influencing factors, may affect the intestinal microbial metabolites, destroy the integrity of the intestinal mucosal barrier and induce intestinal immunity dysfunction, which in turn leads to imbalance of intestinal homeostasis and occurrence of digestive diseases. This article reviews the recent research progress on the effects of high-fat diet on intestinal homeostasis via microbial metabolites.