Advances in the treatment of ovarian cancer with BRCA gene mutation / 中国综合临床
Clinical Medicine of China
;
(12): 470-473, 2021.
Artigo
em Chinês
| WPRIM
| ID: wpr-909780
ABSTRACT
Ovarian cancer is the most fatal malignant tumor in female reproductive system tumors.In most women, it is diagnosed in a late stage, which largely leads to the poor prognosis of ovarian cancer.Breast cancer susceptibility gene (BRCA) is an important DNA homologous repair gene, which plays a major role in the normal cellular DNA repair mechanism.Its mutation will lead to homologous recombination defects, which will affect the stability of the genome and lead to occurrence of tumors.In recent years, BRCA genetic testing has become a key step in the risk assessment, prognosis, treatment and prevention of ovarian cancer.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Tipo de estudo:
Fatores de risco
Idioma:
Chinês
Revista:
Clinical Medicine of China
Ano de publicação:
2021
Tipo de documento:
Artigo
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