Research progress on epigenetics in the repair of radiation-induced DNA damage in tumors / 中华放射肿瘤学杂志
Chinese Journal of Radiation Oncology
;
(6): 1335-1339, 2021.
Artigo
em Chinês
| WPRIM
| ID: wpr-910561
ABSTRACT
Radiotherapy kills tumor cells by radiation-induced DNA double-strand breaks (DSB), however, abnormal DSB repair in tumor cells often leads to radioresistance, in which epigenetics plays an important role. Targeting aberrant epigenetic markers may be a potential means of cancer radiosensitization, but the clinical application of the combination of epigenetic drugs and radiotherapy requires further investigation. This article reviews the latest research progress the role of epigenetics in the repair of radiation-induced DNA damage in tumors.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Idioma:
Chinês
Revista:
Chinese Journal of Radiation Oncology
Ano de publicação:
2021
Tipo de documento:
Artigo
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