Clinicopathological risk factors of retroperitoneal liposarcoma recurrence-free survival after surgical resection / 中华普通外科杂志
Chinese Journal of General Surgery
;
(12): 766-769, 2021.
Artigo
em Chinês
| WPRIM
| ID: wpr-911613
ABSTRACT
Objective:
To explore the clinicopathological risk factors of retroperitoneal liposarcoma recurrence-free survival after surgical resection, and establish a prediction model based on clinicopathological risk factors.Methods:
We conducted a retrospective analysis for retroperitoneal liposarcoma patients undergoing surgical resection at Department of General Surgery, Shanghai Public Health Clinical Center, Zhongshan Hospital (South), Fudan University, during Jul 2014 and Jun 2020. The clinical and pathological data were collected. Univariate and multivariate analysis were used to select independent risk factors.Result:
A total of 271 patients were included, and 127 (46.9%) were recurred. In the recurrence group, more patients were assessed as recurrent disease ( χ2=15.289, P<0.05), the proportion of tumors invading organs was higher ( χ2=10.123, P<0.05), and FNCLCC graded higher ( χ2=7.650, P<0.05). The median follow-up time for all patients was 25 months (1-58 months). The 1, 2, and 3-year recurrence-free survival rates were 61.4%, 40.3%, and 30.9%, respectively. Univariate analysis suggests that recurrent disease, organ invasion, poorly differentiated pathological types, and high FNCLCC grades are poor prognostic factors for postoperative recurrence (all P<0.05); Multivariate analysis showed that recurrent disease ( OR=3.135, 95% CI 2.058-4.762, P<0.05), organ invasion ( OR=2.577, 95% CI 1.214-5.464, P<0.05) and high FNCLCC grade ( P<0.05) is an independent prognostic factor for postoperative recurrence.Conclusion:
Presentation status,FNCLCC grade and organ invasion were independent risk factors for retroperitoneal liposarcoma recurrence after surgery.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Tipo de estudo:
Estudo de etiologia
/
Estudo prognóstico
/
Fatores de risco
Idioma:
Chinês
Revista:
Chinese Journal of General Surgery
Ano de publicação:
2021
Tipo de documento:
Artigo
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