Pay attention to the application of neuromodulation therapy in Parkinson′s disease / 中华神经科杂志

ABSTRACT

There are specific pathological changes in neural circuits and neural network of Parkinson′s disease patients. Neuromodulation therapy can realize the precise treatment of Parkinson′s disease with crucial targets in neural circuits. It is divided into invasive and non-invasive brain stimulation. Invasive brain stimulation mainly refers to deep brain stimulation. The selection of operation time, targets and programming parameters is significant to improve the therapeutic effect of it. Non-invasive brain stimulation mainly includes transcranial magnetic stimulation and transcranial electrical stimulation, which has advantages of safety and strong operability. Comparing to the drug therapy aiming to supply neurotransmitters, neuromodulation therapy has some advantages, and has become a vital option in the precision treatment strategy of Parkinson′s disease.