Research advances on circulating exosomal microRNAs as novel biomarkers of atherosclerotic cardiovascular diseases / 中华检验医学杂志

ABSTRACT

Exosomal microRNAs (miRNAs) from various cell sources in the cardiovascular system are involved in the regulation of diverse biological processes such as angiogenesis, myocardial remodeling, inflammation and plaque rupture, and may function as promising liquid biomarkers for atherosclerotic cardiovascular diseases (ASCVD). Expression analysis of exosomal miRNAs can be employed for monitoring ASCVD progression and evaluating treatment efficiency. This review focused on recent research advances regarding exosomal miRNAs in the field of ASCVD laboratory medicine, and summarized the future research trends and application prospects of circulating exosomal miRNAs in the field of ASCVD.