Efficacy of Oxcarbazepine for Sleep-Related Leg Cramps: A Retrospective Study
Journal of Sleep Medicine
; : 162-166, 2021.
Article
em En
| WPRIM
| ID: wpr-915924
Biblioteca responsável:
WPRO
ABSTRACT
Objectives@#Sleep-related leg cramps (SRLC) are common among older people. Severe clinical symptoms of SRLC usually cause great discomfort to patients. To date, many treatment drugs have been tried; however, there are currently no drugs approved for treating this condition. We aimed to assess the efficacy of a new drug, oxcarbazepine (OXC), in the treatment of SRLC. @*Methods@#We retrospectively analyzed clinical outcomes following OXC administration. A daily dose of 150 mg OXC was prescribed to control nocturnal leg cramps. Clinical outcomes were measured using the Clinical Global Impression Scale to confirm the effectiveness of OXC. @*Results@#A total of 88.9% (16/18) of patients clinically improved four weeks after OXC prescription, and 94% (15/16) of patients continued to improve at the last follow-up (3–6 months). None of the patients complained of side effects related to 150 mg OXC. @*Conclusions@#OXC may be a new medical option for treatment of SRLC.
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Índice:
WPRIM
Tipo de estudo:
Observational_studies
Idioma:
En
Revista:
Journal of Sleep Medicine
Ano de publicação:
2021
Tipo de documento:
Article