Clinical Meaning of Neutrophil-to-Lymphocyte Ratio (NLR)in Papillary Thyroid Carcinoma / 대한내분비외과학회지
Korean Journal of Endocrine Surgery
;
: 31-35, 2016.
Artigo
em Coreano
| WPRIM
| ID: wpr-91779
ABSTRACT
PURPOSE:
Neutrophil-to-lymphocyte ratio (NLR) is a marker of systemic inflammatory response, which is inexpensive, easily calculated, and known to show correlation with prognosis of cancer. The aim of this study was to evaluate the relationship between NLR and prognosis of papillary thyroid carcinoma.METHODS:
A total of 1,142 patients who underwent total thyroidectomy for papillary thyroid carcinoma between 1995~2005 at Asan Medical Center were enrolled in this study. Patients were categorized according to two groups based on NLR and clinico-pathological variables and disease survival were compared between the two groups.RESULTS:
Median age of patients was 45.4 years, and the median follow-up period was 48 months. The cut-off value of NLR for prediction of disease-free survival (DFS) was 2. Comparison of DFS between two groups stratified by NLR (NLR ≤2, NLR>2) showed little statistical difference (P=0.48). After adjusting for risk (N stage), there was no significant difference according to N stage (N0 P=0.86, N1a P=0.4, N1b P=0.12).CONCLUSION:
NLR did not show correlation with disease free survival of papillary thyroid carcinoma.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Prognóstico
/
Glândula Tireoide
/
Tireoidectomia
/
Neoplasias da Glândula Tireoide
/
Seguimentos
/
Intervalo Livre de Doença
Tipo de estudo:
Estudo observacional
/
Estudo prognóstico
/
Fatores de risco
Limite:
Humanos
Idioma:
Coreano
Revista:
Korean Journal of Endocrine Surgery
Ano de publicação:
2016
Tipo de documento:
Artigo
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