Reconstruction and Biomechanical Design of Microvascular Models / 医用生物力学
Journal of Medical Biomechanics
; (6): E180-E185, 2022.
Article
em Zh
| WPRIM
| ID: wpr-920688
Biblioteca responsável:
WPRO
ABSTRACT
Neovascularization plays an important role in many physiological and pathological processes, but its mechanism is still unclear. Since vascular cells are subjected to a variety of biochemical and biomechanical stimulations in vivo and live in a complex microenvironment, it is necessary to construct the vascular model in vitro and simulate the in vivo microenvironment to explore the mechanism of neovascularization. Recently, owing to the advance of micromachining and microfluidic technology, various in vitro microvascular models have emerged. Variables such as shear stress, interstitial flow and biochemical gradient of angiogenic factors have been controlled in these models, which greatly promotes the research of neovascularization. The construction, development and biomechanical design of various microvascular models are reviewed in this paper.
Texto completo:
1
Índice:
WPRIM
Tipo de estudo:
Prognostic_studies
Idioma:
Zh
Revista:
Journal of Medical Biomechanics
Ano de publicação:
2022
Tipo de documento:
Article