Application of CRISPR/Cas-based biosensors for detecting nucleic acid of pathogens / 生物工程学报
Chinese Journal of Biotechnology
;
(12): 3890-3904, 2021.
Artigo
em Chinês
| WPRIM
| ID: wpr-921474
ABSTRACT
Clustered regularly interspaced short palindromic repeats/clustered regularly interspaced short palindromic repeats -associated protein (CRISPR/Cas) has been developed as a precise, efficient, affordable and sensitive nucleic acid detection tool due to its efficient targeted binding ability and programmability. At present, biosensors based on CRISPR-Cas system have shown excellent performance in the detection of nucleic acid of pathogens, which has attracted widespread attention, and is expected to replace the conventional detection methods. This review summarizes the latest research progress of biosensors based on CRISPR/Cas system for detecting nucleic acid of pathogens.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Ácidos Nucleicos
/
Técnicas Biossensoriais
/
Sistemas CRISPR-Cas
Idioma:
Chinês
Revista:
Chinese Journal of Biotechnology
Ano de publicação:
2021
Tipo de documento:
Artigo
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