CRISPR-Cas9: A method for establishing rat models of drug metabolism and pharmacokinetics
Acta Pharmaceutica Sinica B
;
(6): 2973-2982, 2021.
Artigo
em Inglês
| WPRIM
| ID: wpr-922799
ABSTRACT
The 2020 Nobel Prize in Chemistry recognized CRISPR-Cas9, a super-selective and precise gene editing tool. CRISPR-Cas9 has an obvious advantage in editing multiple genes in the same cell, and presents great potential in disease treatment and animal model construction. In recent years, CRISPR-Cas9 has been used to establish a series of rat models of drug metabolism and pharmacokinetics (DMPK), such as
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DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Idioma:
Inglês
Revista:
Acta Pharmaceutica Sinica B
Ano de publicação:
2021
Tipo de documento:
Artigo
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