The effect of a subhypnotic dose of propofol for the prevention of coughing in adults during emergence from anesthesia with sevoflurane and remifentanil / 대한마취과학회지
Korean Journal of Anesthesiology
; : 120-126, 2014.
Article
em En
| WPRIM
| ID: wpr-92343
Biblioteca responsável:
WPRO
ABSTRACT
BACKGROUND: Coughing during emergence from general anesthesia may be detrimental. Propofol is known to inhibit airway reflexes. We evaluated the incidence and severity of coughing in adults who received a subhypnotic dose of propofol at the end of sevoflurane-remifentanil anesthesia. METHODS: Sixty patients, aged 18-65 years, undergoing elective nasal surgery under general anesthesia using sevoflurane and remifentanil were randomly allocated to the propofol group (n = 30) or the control group (n = 30). At the end of surgery, sevoflurane and remifentanil infusion was stopped. After 3 min, the propofol group received propofol 0.3 mg/kg and the control group received normal saline 0.03 ml/kg. The incidence and severity of cough, recovery time and hemodynamic parameters were evaluated during the emergence period. RESULTS: During emergence, the propofol group had the significantly lower incidence (60 vs. 87%) and severity of coughing compared with the control group (P = 0.04, P = 0.02, respectively). There were no significant differences in mean arterial pressure, heart rate, and recovery time during emergence between the two groups. CONCLUSIONS: During emergence from sevoflurane-remifentanil anesthesia, a subhypnotic dose (0.3 mg/kg) of propofol decreases the incidence and severity of coughing without delaying wake up in adults undergoing nasal surgery.
Palavras-chave
Texto completo:
1
Índice:
WPRIM
Assunto principal:
Reflexo
/
Propofol
/
Incidência
/
Tosse
/
Procedimentos Cirúrgicos Nasais
/
Pressão Arterial
/
Frequência Cardíaca
/
Hemodinâmica
/
Anestesia
/
Anestesia Geral
Tipo de estudo:
Incidence_studies
/
Prognostic_studies
Limite:
Adult
/
Humans
Idioma:
En
Revista:
Korean Journal of Anesthesiology
Ano de publicação:
2014
Tipo de documento:
Article