Clinical value of metagenomic next-generation sequencing in complicated infectious diseases / 中国当代儿科杂志
Chinese Journal of Contemporary Pediatrics
;
(12): 210-215, 2022.
Artigo
em Inglês
| WPRIM
| ID: wpr-928589
ABSTRACT
Infectious diseases are commonly seen in clinical practice, and pathogen diagnosis is the key link in diagnosis and treatment; however, conventional pathogen detection methods cannot meet clinical needs due to time-consuming operation and low positive rate. As a new pathogen detection method, metagenomic next-generation sequencing (mNGS) has a wide detection range and can detect bacteria, viruses, fungi, parasites, rare pathogens, and even unknown pathogens. The technique of mNGS is unbiased and can rapidly, efficiently, and accurately obtain all nucleic acid information in test samples, analyze pathogens, and guide clinical diagnosis and treatment, thereby playing an important role in complicated infectious diseases. This article reviews the diagnostic advantages and clinical value of mNGS in bacterial, fungal, viral, and parasitic infections.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Bactérias
/
Doenças Transmissíveis
/
Sensibilidade e Especificidade
/
Metagenômica
/
Sequenciamento de Nucleotídeos em Larga Escala
Tipo de estudo:
Estudo diagnóstico
Limite:
Humanos
Idioma:
Inglês
Revista:
Chinese Journal of Contemporary Pediatrics
Ano de publicação:
2022
Tipo de documento:
Artigo
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