Progress on safety of subcutaneous immunotherapy / 国际儿科学杂志

ABSTRACT

Allergic diseases are a kind of common chronic diseases, whose treatment cycle is long and easy to be repeated, which causes heavy medical and economic burden to the whole world.Allergen immunotherapy(AIT) is the cause-specific therapy for IgE mediated allergic diseases and can change the course of allergic diseases.Although numerous clinical studies have demonstrated the efficacy and safety of AIT in the treatment of allergic diseases, severe and even fatal adverse reactions still occur, especially in subcutaneous immunotherapy(SCIT). This review mainly focuses on the latest research progress of SCIT safety, and summarizes the research status, risk factors, countermeasures and future research directions of SCIT adverse reactions.