Optimization of extraction technology of total saponins from Trillium tschonoskii Rhizome by response surface method / 国际中医中药杂志
International Journal of Traditional Chinese Medicine
;
(6): 56-60, 2022.
Artigo
em Chinês
| WPRIM
| ID: wpr-930099
ABSTRACT
Objective:
To optimize the ethanol reflux extraction process of total saponins in total saponins of Trillium tschonoskii Rhizome.Methods:
On the basis of single factor tests, making the total extraction rate of three main compounds [paris saponin Ⅵ, paris saponin Ⅶ and pennogenin-3- O-α-L-rhamnopyranosyl-(1→4)-[O-α-L-rhamnopyranosyl (1→2)]- O-β-D-glucopyranoside (PRRG)] as the indicator, the optimal extraction parameter was selected with the main influencing factors the ethanol concentration, solid-liquid ratio, and extraction time by the central composite design-response surface method.Results:
The optimal extraction parameter for the ethanol extract of total saponins of Trillium tschonoskii Rhizome was as follows ethanol concentration 69%, extraction time 1.9 h, and solid liquid ratio 1∶9.7. The binomial fitting complex correlation coefficient r = 0.966 1, and the deviation between the extracted predicted value and the actual value is 4.68%.Conclusion:
The central composite design-response surface method is simple and reliable for the optimization of extraction process of total saponins of Trillium tschonoskii Rhizome.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Tipo de estudo:
Estudo prognóstico
Idioma:
Chinês
Revista:
International Journal of Traditional Chinese Medicine
Ano de publicação:
2022
Tipo de documento:
Artigo
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