The remedial surgery for parathyroid carcinoma / 中华内分泌外科杂志

ABSTRACT

The incidence of parathyroid carcinoma (PC) is low while the long-term outcome is poor in most cases. Most patients with PC suffered from relapse or metastasis, and the main reason of mortality is hypercalcemia and related complications. Surgery is the main therapy for PC. Local resection is suitable for benign lesion while radical resection including parathyroid lesion, ipsilateral thyroid lobe and surrounding soft tissue is suggested for parathyroid carcinoma. It is still difficult to identify the malignancy among parathyroid neoplasm before operation without distant metastasis. Parathyroid carcinoma was diagnosed after first surgery of local resection in most patients with histopathological evaluation. The significance of remedial surgery for this situation was still indeterminate. In this review, the different opinions about the management of PC were introduced and several suggestions were presented based on the literatures.