Comparison of short and long term curative effect between conservative and interventional therapy in Fontaine stage Ⅱ patients with lower extremity arteriosclerosis obliterans / 中华普通外科杂志

ABSTRACT

Objective:To compare the short-and long-term effects of conservative and interventional treatment in patients with lower extremity arteriosclerosis obliterans of Fontaine stage Ⅱ.Methods:This is a retrospective analysis,184 patients (219 limbs) admitted to the Department of Vascular Surgery, First Affiliated Hospital of Shandong First Medical University from Jun 2014 to Jun 2017, were divided into the conservative treatment group (93 limbs) and interventional treatment group (126 limbs).Results:The short-term effective rate in the intervention group was better than that of the conservative group (83.33% vs. 45.16%, P<0.05). After one year follow-up, the total effective rate in the groups was similar (60.32% vs. 53.76%, P>0.05). While the total effective rate of the conservative group was better than that of the intervention group (60.21% vs. 53.17%) after the 3-year follow-up,though the differences were not statistically significant ( P>0.05). The rates of all-cause death, amputation, and cardiovascular events in the conservative group were lower; though the difference was not significant ( P>0.05). However, the intervention group had a significantly higher rate of restenosis and re-intervention rate during the 3-year follow-up period ( P<0.05). Conclusion:Compared to intervention group,the conservative treatment is more economical ,effective and safe for patients with lower extremity arteriosclerosis obliterans of Fontaine stage Ⅱ.