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Dynamic Contrast-Enhanced MR Imaging in Detecting Local Tumor Progression after HIFU Ablation of Localized Prostate Cancer
Journal of the Korean Society of Magnetic Resonance in Medicine ; : 192-199, 2013.
Artigo em Inglês | WPRIM | ID: wpr-93362
ABSTRACT

PURPOSE:

To retrospectively evaluate the diagnostic performance of dynamic contrast-enhanced MR imaging (DCE-MRI) in detecting recurrent prostate cancer after HIFU of clinically localized cancer, as compared with T2-weighted imaging (T2WI). MATERIALS AND

METHODS:

Twenty-six patients with increased prostate-specific antigen levels after HIFU were included in this study. All MR examinations were performed using T2WI and DCE-MRI, followed by transrectal ultrasound-guided biopsy. MRI and biopsy results were correlated in six prostate sectors. Residual or recurrent cancer after HIFU was defined as local tumor progression if biopsy results showed any cancer foci. Two independent readers interpreted the MR images.

RESULTS:

Of 156 prostate sectors, 51 (33%) were positive for cancer in 17 patients. For detecting local tumor progression, the sensitivity of DCE-MRI and T2WI was 80% and 57% for reader 1 (P 0.05). Interobserver agreement of DCE-MRI and T2WI was moderate and fair, respectively.

CONCLUSION:

For detecting local tumor progression of prostate cancer after HIFU, DCE-MRI was more sensitive than T2WI, with less interobserver variability.
Assuntos

Texto completo: DisponíveL Índice: WPRIM (Pacífico Ocidental) Assunto principal: Próstata / Neoplasias da Próstata / Biópsia / Variações Dependentes do Observador / Estudos Retrospectivos / Sensibilidade e Especificidade / Antígeno Prostático Específico Tipo de estudo: Estudo diagnóstico / Estudo observacional Limite: Humanos Idioma: Inglês Revista: Journal of the Korean Society of Magnetic Resonance in Medicine Ano de publicação: 2013 Tipo de documento: Artigo

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Texto completo: DisponíveL Índice: WPRIM (Pacífico Ocidental) Assunto principal: Próstata / Neoplasias da Próstata / Biópsia / Variações Dependentes do Observador / Estudos Retrospectivos / Sensibilidade e Especificidade / Antígeno Prostático Específico Tipo de estudo: Estudo diagnóstico / Estudo observacional Limite: Humanos Idioma: Inglês Revista: Journal of the Korean Society of Magnetic Resonance in Medicine Ano de publicação: 2013 Tipo de documento: Artigo