Comparative analysis of economics of hypothermic mechanical perfusion versus static cold preservation for kidney transplantation / 中华器官移植杂志

ABSTRACT

Objective:An assessment of domestic and foreign literatures regarding the medical expenses of kidney hypothermic machine perfusion(HMP)versus cold storage(CS)to provide guidance for clinical decision-making.Methods:Relevant literatures were retrieved from PubMed, CENTRAL(Cochrane Library), Web of Science, EMBASE, CNKI, Wanfang, etc.The literatures and according data were finally enrolled based on the inclusion and exclusion criteria.The results were reported descriptively.Results:A total of 10 literatures reporting the costs of HMP and CS were included.The results show that HMP can reduce the cost of first hospitalization compared with CS in expanded criteria donor.HMP may also reduce long-term costs compared to CS.The lower cost may be associated with the lower incidence of delayed graft function(DGF).Conclusions:HMP may bring medical and economic benefits to patients.The cost advantage of HMP over CS may be related to the improved quality of donor kidney and a lower incidence of DGF.