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A comprehensive overview of RET fusion lung caner’s characters, diagnosis and treatment / 中华胸心血管外科杂志
Chinese Journal of Thoracic and Cardiovascular Surgery ; (12): 305-309, 2022.
Artigo em Chinês | WPRIM | ID: wpr-934249
ABSTRACT
The RET(REarranged during transfection) gene as a novel has broken the therapeutic deadlock in the last two years, whith is attributed to the rapid approval of targeted therapies and inclusion in treatment guidelines, bringing more hope for the survival of patients with non-small cell lung cancer(NSCLC). Usually, the main activation of the RET proto-oncogene contributes to the development of lung cancer via somatic rearrangements. Thus, this study reviews the biological characteristics of RET gene, the classification of RET fusion in lung cancer and the detection of RET fusion. Meanwhile the pathological and clinical features, targeted therapies, drug resistance, prognosis of lung cancer patients with RET fusion were further discussed.
Texto completo: DisponíveL Índice: WPRIM (Pacífico Ocidental) Tipo de estudo: Estudo diagnóstico / Guia de Prática Clínica / Estudo prognóstico Idioma: Chinês Revista: Chinese Journal of Thoracic and Cardiovascular Surgery Ano de publicação: 2022 Tipo de documento: Artigo

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Texto completo: DisponíveL Índice: WPRIM (Pacífico Ocidental) Tipo de estudo: Estudo diagnóstico / Guia de Prática Clínica / Estudo prognóstico Idioma: Chinês Revista: Chinese Journal of Thoracic and Cardiovascular Surgery Ano de publicação: 2022 Tipo de documento: Artigo