Your browser doesn't support javascript.
loading
A panel study on the acute respiratory effects of ambient particles of different sizes on children in Shanghai / 中华预防医学杂志
Chinese Journal of Preventive Medicine ; (12): 322-327, 2022.
Artigo em Chinês | WPRIM | ID: wpr-935287
ABSTRACT

Objective:

To explore the association between size-fractionated particle number concentrations (PNC) and respiratory health in children.

Methods:

From November 2018 to June 2019, there were 65 children aged 6-9 years from an elementary school in shanghai recruited in this panel study with three rounds of follow-up. The forced vital capacity (FVC), forced expiratory volume in the first second (FEV1), and exhaled nitric oxide (FeNO) levels were measured and buccal mucosa samples of children were collected at each follow-up visit. The level of PNC, temperature and humidity of the elementary school was monitored from 3 days before each physical examination to the end of the physical examination. The linear mixed effects model was used to analyze the association between PNC and indicators of respiratory health in children.

Results:

Linear mixed effects model analysis revealed that, at lag 2 day, an interquartile range increase in PNC for particles measuring 0.25-0.40 μm was associated with the absolute changes in FVC, FEV1 and abundance-based coverage estimator (ACE) about -60.15 ml (95%CI-88.97 ml, -31.32 ml), -34.26 ml (95%CI-63.22 ml, -5.31 ml), -6.00 (95%CI-9.15, -2.84) and percentage change in FeNO about 12.10% (95%CI 3.05%, 21.95%), respectively. These adverse health effects increased with the decrease of particle size.

Conclusion:

The short-term exposure to particulate matter is associated with reduced lung function, buccal microbe diversity and higher airway inflammation level among children. These adverse health effects may increase with the decrease of particle size.
Assuntos
Texto completo: DisponíveL Índice: WPRIM (Pacífico Ocidental) Assunto principal: China / Capacidade Vital / Poluentes Atmosféricos / Exposição Ambiental / Material Particulado / Pulmão / Óxido Nítrico Limite: Criança / Humanos País/Região como assunto: Ásia Idioma: Chinês Revista: Chinese Journal of Preventive Medicine Ano de publicação: 2022 Tipo de documento: Artigo

Similares

MEDLINE

...
LILACS

LIS

Texto completo: DisponíveL Índice: WPRIM (Pacífico Ocidental) Assunto principal: China / Capacidade Vital / Poluentes Atmosféricos / Exposição Ambiental / Material Particulado / Pulmão / Óxido Nítrico Limite: Criança / Humanos País/Região como assunto: Ásia Idioma: Chinês Revista: Chinese Journal of Preventive Medicine Ano de publicação: 2022 Tipo de documento: Artigo