Invasive Fungal Sinusitis of the Sphenoid Sinus
Clinical and Experimental Otorhinolaryngology
; : 181-187, 2014.
Article
em En
| WPRIM
| ID: wpr-93547
Biblioteca responsável:
WPRO
ABSTRACT
OBJECTIVE: This study was conducted to present the clinical outcome of invasive fungal sinusitis of the sphenoid sinus and to analyze clinical factors influencing patient survival. METHODS: A retrospective review of 12 cases of invasive fungal sphenoiditis was conducted. RESULTS: Cases were divided into acute fulminant invasive fungal spheonoidits (n=4) and chronic invasive fungal sphenoiditis (n=8). The most common underlying disease was diabetes mellitus (n=9). The most common presenting symptoms and signs included visual disturbance (100%). Intracranial extension was observed in 8 patients. Endoscopic debridement and intravenous antifungals were given to all patients. Fatal aneurysmal rupture of the internal carotid artery occurred suddenly in two patients. The mortality rate was 100% for patients with acute fulminant invasive fungal sphenoiditis and 25% for patients with chronic invasive fungal sphenoiditis. In survival analysis, intracranial extension was evaluated as a statistically significant factor (P=0.027). CONCLUSION: The survival rate of chronic invasive fungal sphenoiditis was 75%. However, the prognosis of acute fulminant invasive fungal sphenoiditis was extremely poor despite the application of aggressive treatment, thus, a high index of suspicion should be required and new diagnostic markers need to be developed for early diagnosis of invasive fungal sinusitis of the sphenoid sinus.
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Índice:
WPRIM
Assunto principal:
Prognóstico
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Ruptura
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Sinusite
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Seio Esfenoidal
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Artéria Carótida Interna
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Taxa de Sobrevida
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Estudos Retrospectivos
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Mortalidade
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Desbridamento
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Diagnóstico Precoce
Tipo de estudo:
Diagnostic_studies
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Observational_studies
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Prognostic_studies
/
Screening_studies
Limite:
Humans
Idioma:
En
Revista:
Clinical and Experimental Otorhinolaryngology
Ano de publicação:
2014
Tipo de documento:
Article